Stephen T Talcott Selected Research

Hydrolyzable Tannins

1/2020	Mango (Mangifera indica L.) polyphenols reduce IL-8, GRO, and GM-SCF plasma levels and increase Lactobacillus species in a pilot study in patients with inflammatory bowel disease.
1/2019	Gallotannins and Lactobacillus plantarum WCFS1 Mitigate High-Fat Diet-Induced Inflammation and Induce Biomarkers for Thermogenesis in Adipose Tissue in Gnotobiotic Mice.
9/2016	Pyrogallol, an absorbable microbial gallotannins-metabolite and mango polyphenols (Mangifera Indica L.) suppress breast cancer ductal carcinoma in situ proliferation in vitro.
1/2016	Comparison of anti-inflammatory mechanisms of mango (Mangifera Indica L.) and pomegranate (Punica Granatum L.) in a preclinical model of colitis.
8/2015	Mango polyphenolics suppressed tumor growth in breast cancer xenografts in mice: role of the PI3K/AKT pathway and associated microRNAs.

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Stephen T Talcott Research Topics

Disease

10	Inflammation (Inflammations) 05/2021 - 07/2011
10	Neoplasms (Cancer) 01/2017 - 08/2003
4	Ulcerative Colitis 12/2021 - 01/2016
3	Colitis 01/2020 - 01/2016
3	Obesity 01/2019 - 05/2018
3	Colonic Neoplasms (Colon Cancer) 01/2017 - 05/2008
3	Breast Neoplasms (Breast Cancer) 01/2017 - 08/2015
3	Leukemia 02/2006 - 08/2003
2	Carcinogenesis 01/2020 - 10/2016
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 06/2018 - 12/2013
2	Noninfiltrating Intraductal Carcinoma (DCIS) 01/2017 - 09/2016
2	Hypoxia (Hypoxemia) 10/2016 - 08/2015
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2020
1	Insulin Resistance 01/2019
1	Chronic Disease (Chronic Diseases) 05/2018
1	Constipation 01/2018
1	Adenocarcinoma 01/2017
1	Aberrant Crypt Foci 10/2016
1	Colorectal Neoplasms (Colorectal Cancer) 01/2016
1	Alzheimer Disease (Alzheimer's Disease) 02/2013
1	Dementia (Dementias) 02/2013
1	Tics (Tic) 01/2013
1	Carcinoma (Carcinomatosis) 07/2006

Drug/Important Bio-Agent (IBA)

16	PolyphenolsIBA 12/2021 - 08/2003
6	Gallic AcidIBA 01/2020 - 07/2011
5	Biomarkers (Surrogate Marker)IBA 01/2020 - 01/2018
5	Hydrolyzable TanninsIBA 01/2020 - 08/2015
3	Proteins (Proteins, Gene)FDA Link 10/2016 - 07/2011
3	Ellagic AcidIBA 07/2006 - 08/2003
2	Dietary Fiber FDA Link 05/2021 - 01/2018
2	Tannic Acid FDA Link 01/2020 - 05/2018
2	CytokinesIBA 01/2020 - 01/2016
2	EnzymesIBA 01/2019 - 01/2013
2	Anthocyanins (Anthocyanin)IBA 11/2018 - 01/2017
2	Glucose (Dextrose)FDA LinkGeneric 06/2018 - 07/2011
2	Dextrans (Dextran)FDA Link 01/2017 - 01/2016
2	PyrogallolIBA 01/2017 - 09/2016
2	LipopolysaccharidesIBA 01/2017 - 07/2011
2	sodium sulfate (sodium bisulfate)FDA LinkGeneric 01/2017 - 01/2016
2	MicroRNAs (MicroRNA)IBA 10/2016 - 08/2015
2	Messenger RNA (mRNA)IBA 10/2016 - 08/2015
2	TOR Serine-Threonine KinasesIBA 10/2016 - 08/2015
2	PhytochemicalsIBA 05/2008 - 01/2004
2	AntioxidantsIBA 05/2008 - 07/2006
2	QuercetinIBA 03/2005 - 08/2003
1	3-hydroxybenzeneacetic acidIBA 12/2021
1	16S Ribosomal RNAIBA 12/2021
1	PrebioticsIBA 05/2021
1	Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF)IBA 01/2020
1	Interleukin-8 (Interleukin 8)IBA 01/2020
1	tannaseIBA 01/2019
1	LipidsIBA 06/2018
1	Interleukin-6 (Interleukin 6)IBA 01/2018
1	GastrinsIBA 01/2018
1	Volatile Fatty AcidsIBA 01/2018
1	EndotoxinsIBA 01/2018
1	n-pentanoic acid (valeric acid)IBA 01/2018
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2017
1	70-kDa Ribosomal Protein S6 Kinases (Ribosomal Protein S6 Kinases, 70 kDa)IBA 01/2017
1	polypeptide 1 70kD ribosomal protein S6 kinaseIBA 01/2017
1	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 10/2016
1	Fluorouracil (Carac)FDA LinkGeneric 09/2016
1	TanninsIBA 01/2016
1	NF-kappa B (NF-kB)IBA 08/2015
1	Phosphatidylinositols (Phosphatidylinositol)IBA 08/2015
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 08/2015
1	ResveratrolIBA 12/2013
1	Grape Seed ExtractIBA 12/2013
1	Intercellular Adhesion Molecule-1 (Intercellular Adhesion Molecule 1)IBA 07/2011
1	Platelet Endothelial Cell Adhesion Molecule-1IBA 07/2011
1	3-hydroxyflavoneIBA 06/2011
1	GlycosidesIBA 02/2006
1	Phosphotransferases (Kinase)IBA 03/2005

Therapy/Procedure

1	Therapeutics 01/2020
1	Subcutaneous Injections 10/2016